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ERA-EDTA WORKING GROUP ON CHRONIC KIDNEY DISEASE AND MINERAL BONE DISORDER (CKD-MBD)

CKD-MBD is an official working group of ERA-EDTA ERA-EDTA
CKD-MBD NEWS
CKD-MBD Newsletter #6 (2), 2016
CKD-MBD related publications #6 (Nephrol Dial Transplant and Clin Kidney J)
THE KDIGO CKD-MBD GUIDELINE UPDATE
IS NOW AVAILABLE FOR PUBLIC REVIEW
TEN REASONS TO BECOME A MEMBER OF THE CKD-MBD WORKING GROUP
CKD-MBD WG Symposium: New Insights into CKD-MBD
ERA-EDTA Congress 2017,  3-6 June, (Madrid, Spain)
Multinational EuCalNet (European Calciphylaxis Network) Initiative
International patient registration (secure server)
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Bone: a new endocrine organ at the heart of chronic kidney disease and mineral and bone disorders
The Lancet Diabetes & Endocrinology Volume 2, Issue 5, Pages 427 - 436, May 2014

Is chronic kidney disease-mineral bone disorder (CKD-MBD) really a syndrome?
Nephrol Dial Transplant 2014 (free full text)
  
The ERA-EDTA Council recently approved the creation of a working group dedicated to Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). This acronym, or its translation, has been increasingly endorsed by different Nephrology Societies and International initiatives, including both the KDIGO (Kidney Disease Improving Global Outcomes) and the EBPG (European Best Practice Guidelines).

The definition of CKD-MBD is different than the previously recognized as "renal osteodystrophy", and it refers to a systemic disorder of mineral and bone metabolism due to CKD manifested by either one or a combination of the following:

  • Abnormalities of calcium, phosphorus, parathyroid hormone (PTH), or vitamin D metabolism.
  • Abnormalities in bone turnover, mineralization, volume, linear growth, or strenght.
  • Vascular or other soft-tissue calcification.

The term "renal osteodystrophy" is now limited to an alteration of bone morphology in patients with CKD, and it is one measure of the skeletal component of the systemic disorder of CKD-MBD that is quantifiable by histomorphometry of bone biopsy.

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Thus, the CKD-MBD Working Group becomes an independent scientific organization comprising a group of European academic medical institutions aligned to CKD-MBD regarding:

  • Enhancing the scientific understanding and preclinical background.
  • Analyzing the clinical implications.
  • Elaborating therapeutic options.
Special emphasis is on:
  • Increasing research collaborations.
  • Promote education for Fellows and Faculty.
  • Improve scientific communication and dissemination of knowledge in the field.

HISTORY OF THE GROUP
AIMS

As per the ERA-EDTA regulations for Working groups, the vision and mission of the CKD-MBD Working Group are:

  • To promote and organize pan-European independent research in the field of CKD-MBD including both basic, translational and clinical research.
  • To improve and distribute knowledge in the field of CKD-MBD (appropriate therapies, Guidelines, etc.).
  • To address particular research questions that have not and may not be addressed by usual means.
  • To organize a structured educational process and program for young researchers in the field of CKD-MBD allowing them to start networking and exchange expertise.
  • To collaborate to the organization of educational activities of the ERA-EDTA.
  • To develop training concepts for both clinical as well as research activities throughout Europe.
  • To organize an annual meeting focusing on educational themes and on research proposals.
  • To organize an annual meeting during the annual ERA-EDTA Congress, to be included in the Scientific Program.